Hello,
Image size: there is no real limitation in IM, it will depend on your RAM.
May be the opening of the magnifier window will be slower, as it opens the image at its full resolution, for precise placement.
To be sure that your display is not too slow, you can set in the preferrences a proxy size to use (for the viewports textures and background). This is only a display restriction, we do not resize your image.
12mm lens: I do not know this lens, but I guess there will be some distortion. I recommend to calibrate a special project to find out your internal parameters at 12mm (focal really 12mm ?, and distortion).
I will create a new post, as mcah also ask for it, to explain how using grids in different plane can be used to calibrate your internal params.
Re-locating in photoshop is at your own risk :-), I do not recommend it.
Re-calibrate pb : I suggest you send the project before (green) and after (red) to support@realviz.com
Hope it helps,
Stef